PROJECTS:
Hindbrain patterning
Evo-devo
Pancreas development

PROJECTS: Pancreas development

Mary Kinkel - Research Associate (Assistant Professor), Department of Organismal Biology and Anatomy
Gokhan Dalgin - JDRF Postdoctoral Fellow, Department of Organismal Biology and Anatomy
Stefani Eames - Graduate student, Committee on Molecular Metabolism and Nutrition
Ranjani Logaraj - Undergraduate Student, Department of Organismal Biology and Anatomy
Crystal Love - Graduate student, Committee on Developmental Biology

Mary Kinkel   

I am pursuing two general themes:

1. How is pancreatic islet location and size determined during embryonic development?
This work focuses on the mechanisms by which beta-cell mass is limited by the cdx4 transcription factor during early pancreas development.

2. How do small, non-lethal developmental perturbations affect beta-cell function during adulthood?
Beta-cells lower blood glucose by releasing insulin into circulation. To study beta-cell function, I am using adult zebrafish as a model for studying the maintenance of blood glucose homeostasis.

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